METHUSELAH ARCHIVE CLAIMS
Claims

What they actually said.

160 specific claims made for the interventions — each tagged by endpoint type and whether it was refuted, replicated, or never tested. The archive's record of the promises.
1558 · untested
La vita sobria (Cornaro's sober diet)
The sober diet cured the grave illnesses of Cornaro's fortieth year and restored him to health and vigour.
1558 · untested
La vita sobria (Cornaro's sober diet)
Strict moderation in food is a universally applicable 'divine medicine' that conserves the body and lengthens every life, not only Cornaro's.
1558 · untested
La vita sobria (Cornaro's sober diet)
A fixed, spare daily diet (the sober life) wards off disease and prolongs life into vigorous old age, as in Cornaro's own long life.
1779 · refuted
Animal magnetism (mesmerism)
Treatment around the magnetized baquet apparatus, under the guidance of a trained operator, will cure or substantially relieve a broad range of…
1779 · refuted
Animal magnetism (mesmerism)
There exists a universal physical fluid, analogous to gravity or electricity, that pervades all living bodies; illness is a blockage of this fluid's…
1780 · refuted
Egyptian physical regeneration and the Wine of Egypt
A few drops of the 'Wine of Egypt', taken at the prescribed phase of the moon, rejuvenate the body and restore lost youth.
1781 · untested
Celestial Bed and Temple of Health
James Graham's Grand State Celestial Bed, hired by the night at his Temple of Hymen at Schomberg House on Pall Mall from June 1781, used insulated…
1781 · untested
Celestial Bed and Temple of Health
Graham's branded preparations (the Wikipedia biography records the two principal advertised names as Electrical Aether and Nervous Aetherial Balsam)…
1783 · refuted
Animal magnetism (mesmerism)
The mesmeric procedure, including the baquet sessions and the intimate hand-pass treatment by the operator, is safe and presents no significant…
1784 · refuted
Egyptian physical regeneration and the Wine of Egypt
Cagliostro's Egyptian arcana confer a span of life far beyond the natural one, approaching the 'beginning of immortality'.
1784 · refuted
Celestial Bed and Temple of Health
The Temple of Health and Temple of Hymen enterprise did not survive its first four London years: James Graham was reported bankrupt by 1782 in the…
1784 · refuted
Egyptian physical regeneration and the Wine of Egypt
Cagliostro's forty-day 'physical regeneration' retreat restores the body to the purity and vigour of youth and renews the adept for a further span…
1784 · replicated
Magnetic somnambulism (artificial somnambulism)
Magnetizing a patient by passes of the hands and directed will induces a distinct sleep-like lucid state (artificial or magnetic somnambulism),…
1784 · refuted
Magnetic somnambulism (artificial somnambulism)
Animal magnetism, applied through the induction of magnetic somnambulism, cures disease in the patient.
1784 · refuted
Magnetic somnambulism (artificial somnambulism)
In magnetic somnambulism the entranced subject acquires a lucid faculty to perceive and diagnose disease, in themselves and in others, and to…
1796 · refuted
Perkins Metallic Tractors
The Perkins Metallic Tractors, drawn across the skin over an affected body part for approximately twenty minutes, relieve rheumatism, gout,…
1796 · unreplicated
Homeopathy (Hahnemann's system of medicine)
A drug that produces a particular set of symptoms in a healthy person is the remedy that will cure a disease presenting with similar symptoms…
1796 · refuted
Cordial Balm of Gilead
The Cordial Balm of Gilead is a unique medicine of the choicest balsams, the sole invention of Dr Solomon, prepared by a long and laborious secret…
1797 · untested
Macrobiotics (Hufeland's art of prolonging life)
An advanced old age is attainable through abstemious macrobiotic living, as illustrated by the long life attributed to the spare daily diet of the…
1797 · untested
Macrobiotics (Hufeland's art of prolonging life)
Retarding the consumption of the vital force through a regimen of moderation in diet, regular sleep, pure air, exercise, and tranquillity of mind…
1797 · refuted
Macrobiotics (Hufeland's art of prolonging life)
The duration of human life is governed by an innate vital power (Lebenskraft): life is the operation of that power, vital operation consumes it, and…
1799 · replicated
Perkins Metallic Tractors
Fictitious tractors of wood, carved to resemble the patented Perkins metallic pair, produce the same patient-reported relief as the original…
1799 · refuted
Cordial Balm of Gilead
The Cordial Balm of Gilead relieves and cures nervous disorders, debility, lowness of spirits, weaknesses, and a long list of further complaints…
1799 · refuted
Cordial Balm of Gilead
The Cordial Balm of Gilead restores impaired vigour and renews 'impaired and tottering constitutions', bracing and invigorating the nervous system…
1800 · replicated
Perkins Metallic Tractors
Imagination and expectation can produce not only the relief of symptoms reported by satisfied patients but also the worsening of symptoms in a small…
1801 · refuted
Brodum's Restorative Nervous Cordial and Botanical Syrup
Brodum's advertising claims his medicines reverse the debility produced by the indiscretions of youth, assuring readers that constitutions ruined by…
1801 · refuted
Brodum's Restorative Nervous Cordial and Botanical Syrup
Brodum's Restorative Nervous Cordial preserves health into advanced age and wards off decline: by it 'the health of thousands' has been 'preserved…
1801 · refuted
Brodum's Restorative Nervous Cordial and Botanical Syrup
Brodum's Nervous Cordial restores weakly and debilitated constitutions, bracing the system and giving it 'vigour to the functions of life', and…
1810 · refuted
Homeopathy (Hahnemann's system of medicine)
Homeopathic treatment cures disease through a specific action of the potentized remedy, beyond any placebo effect.
1810 · refuted
Homeopathy (Hahnemann's system of medicine)
Diluting a medicine in repeated steps with succussion (potentization) increases its curative power, even past the point at which no molecule of the…
1827 · refuted
St John Long's Corrosive Liniment and Inhalation
In cases of internal disease, creating an external wound and a discharge on the skin carries the malady out of the body, curing or preventing…
1828 · refuted
Morison's Vegetable Universal Medicine (Hygeian pills)
All disease arises from a single cause, the impurity of the blood, and the Vegetable Universal Medicine cures every disease by purging that impurity…
1828 · refuted
Morison's Vegetable Universal Medicine (Hygeian pills)
Continued purging with the pills keeps the blood pure and thereby preserves health and prevents disease, the Hygeian route to lasting health and…
1828 · refuted
Morison's Vegetable Universal Medicine (Hygeian pills)
The pills are harmless in any quantity, so larger and more frequent doses produce a fuller cure without risk.
1830 · refuted
St John Long's Corrosive Liniment and Inhalation
The liniment is harmless when applied to healthy skin but produces its wound-raising effect only where it overlies a diseased organ, so that its…
1830 · refuted
St John Long's Corrosive Liniment and Inhalation
Favourable testimony from Long's other patients, including titled society figures, proves the treatment's safety and efficacy.
1832 · refuted
Grahamism (the Graham system of diet and hygiene)
Stimulation of the nervous system by 'unnatural' food, drink, tobacco, and sexual activity is itself a cause of disease; a plain diet and total…
1834 · refuted
Grahamism (the Graham system of diet and hygiene)
Masturbation ('the solitary vice') inflames the nervous system and brain more severely than any other form of sexual activity, producing progressive…
1837 · untested
Grahamism (the Graham system of diet and hygiene)
Strict adherence to the Graham system (whole-wheat bread, vegetables, cold water, total abstinence from stimulants, and sexual restraint) preserves…
1837 · replicated
Grahamism (the Graham system of diet and hygiene)
Bread made from coarse, unbolted whole-wheat flour, eaten as the dietary staple, is more healthful than bread made from refined ('bolted') white…
1842 · unreplicated
The cold-water cure (Gräfenberg hydropathy)
The Gräfenberg cold-water cure relieves or cures chronic and acute disease across a wide range of conditions, succeeding where conventional drug…
1842 · refuted
The cold-water cure (Gräfenberg hydropathy)
Disease is caused by morbid (peccant) matter lodged in the body, and the cold-water cure works by mobilizing that matter and driving it out through…
1847 · refuted
Liebig's Extractum Carnis (LEMCO)
Meat extract contains the essential nitrogenous albuminoids and kreatin that constitute meat's vital nutritive principles; consuming the extract…
1847 · unreplicated
The cold-water cure (Gräfenberg hydropathy)
Beyond water applications, recovery at Gräfenberg required a prescribed regimen of movement therapy, air and sun baths, and a spare diet (cold-water…
1865 · refuted
Liebig's Extractum Carnis (LEMCO)
One pound of Liebig's Extract of Meat represents the concentrated nutritive value of 34 pounds of fresh beef; invalids and convalescents can obtain…
1865 · refuted
Liebig's Extractum Carnis (LEMCO)
Liebig's meat extract, taken as meat tea, is a medicinal food for invalids and the sick, marketed through physicians as a restorative for those too…
1886 · unreplicated
Kneipp Cure (hydrotherapy, herbalism, and the 'five pillars')
Brief applications of cold water, by provoking a generalized circulatory 'reaction' in the body, treat or prevent an unusually wide, largely…
1887 · refuted
Wm. Radam's Microbe Killer
The Microbe Killer cures all diseases (the jugs were lettered 'CURES ALL DISEASES'), from consumption and rheumatism to any complaint a doctor has…
1889 · refuted
Brown-Séquard testicular extract (organotherapy)
The testicular-extract protocol reverses the effects of aging in elderly recipients, restoring functional capacities of younger age and extending…
1889 · refuted
Brown-Séquard testicular extract (organotherapy)
Subcutaneous injection of aqueous extract from animal testes restores physical strength, mental acuity, and general functional capacity in older men…
1890 · refuted
Arsenic slimming and complexion nostrums
Arsenic clears and whitens the complexion, removing blemishes and producing fresh, fair skin.
1890 · refuted
Arsenic slimming and complexion nostrums
Taken in small regular doses, arsenic is safe and produces its benefits without lasting harm.
1890 · refuted
Arsenic slimming and complexion nostrums
Small regular doses of arsenic stimulate the system, carry off surplus flesh, and produce a slender figure.
1890 · refuted
Brown-Séquard testicular extract (organotherapy)
The testicular-extract injection protocol is safe; the preparation does not produce significant adverse reactions and the procedure presents no…
1890 · refuted
Wm. Radam's Microbe Killer
There is but one disease, caused by microbes, and the Microbe Killer cures every illness by destroying the microbes in the body; as Radam put it,…
1890 · refuted
Wm. Radam's Microbe Killer
The Microbe Killer contains no drugs and is harmless: in Radam's words it 'is pure water, permeated with gases ... in which micro-organisms cannot…
1891 · refuted
Lahmann's Physiatric Regimen (dietetic blood-dyscrasia cure)
Improper diet produces an abnormal ('dyscrasic') composition of the blood, which in turn produces a corresponding faulty composition of every body…
1894 · refuted
J.B.L. ('Joy, Beauty, Life') Cascade internal bath
Regular use of the J.B.L. Cascade internal bath will infallibly confer 'Joy, Beauty, Life,' being the one safe and sanative method of regaining and…
1894 · refuted
Spermin-Poehl (Sperminum-Poehl) organotherapy
Spermin acts as a catalytic agent that increases oxidation in the tissues and as a physiological antitoxin that neutralizes 'autointoxication'…
1894 · refuted
J.B.L. ('Joy, Beauty, Life') Cascade internal bath
There is only one cause of disease, the retention of waste matters in the system (intestinal autointoxication); clearing the colon therefore removes…
1897 · unreplicated
Marine plasma (Sérum de Quinton)
An animal's entire blood volume can be replaced with sterilized isotonic seawater without fatal outcome, demonstrating that seawater is…
1897 · refuted
The Kuhne friction sitz bath and 'New Science of Healing'
Internal disease can be read from the face and body: deposits of foreign matter produce visible swellings and changes ('encumbrances') that reveal…
1898 · unreplicated
Lahmann's Physiatric Regimen (dietetic blood-dyscrasia cure)
Systematic exposure of the unclothed body to air and sunlight ('airbath') hardens the body and functions as a means of healing, over and above…
1898 · refuted
Spermin-Poehl (Sperminum-Poehl) organotherapy
Administration of spermin ('Sperminum-Poehl') restores vital energy and checks senile decline, because the body's spermin diminishes with age and…
1898 · refuted
Spermin-Poehl (Sperminum-Poehl) organotherapy
Injected Sperminum-Poehl is an effective treatment for senile debility, neurasthenia, convalescent exhaustion, and male sexual weakness, across a…
1898 · unreplicated
Lahmann's Physiatric Regimen (dietetic blood-dyscrasia cure)
Conventional tight-fitting clothing impairs circulation and contributes to disease; Lahmann's own loose-weave, all-cotton reform underwear ('Dr.…
1900 · unreplicated
Physical Culture (Macfadden's drugless system)
Regular vigorous exercise and a moderate diet improve physical fitness and general health.
1900 · refuted
Physical Culture (Macfadden's drugless system)
Fasting, together with hydropathy and exercise, cures chronic and acute disease and is a substitute for physicians and drugs ('the fasting cure').
1901 · refuted
The Kuhne friction sitz bath and 'New Science of Healing'
All disease has a single cause, the accumulation of 'foreign matter' (a self-poisoning of the body), and therefore a single cure: there is a unity…
1901 · refuted
The Kuhne friction sitz bath and 'New Science of Healing'
The friction sitz bath (Sitzreibebad), in which the bather sits in cold water and gently rubs the external genital region with a cloth for ten to…
1903 · replicated
Fletcherism (thorough mastication)
Prolonged, thorough chewing reduces the quantity of food a person eats.
1904 · refuted
Marine plasma (Sérum de Quinton)
All animal cells retain a 'marine milieu' identical in mineral composition to primordial seawater because life originated in the sea; therefore…
1905 · refuted
J.B.L. ('Joy, Beauty, Life') Cascade internal bath
Internal bathing with the J.B.L. Cascade prevents or cures appendicitis and a wide range of other diseases.
1906 · unreplicated
Marine plasma (Sérum de Quinton)
Subcutaneous or intravenous injections of isotonic seawater ('marine plasma') successfully treated infant enteritis, cholera-type diarrheal illness,…
1907 · unreplicated
Bennett's rejuvenation system (muscular contractions and self-massage)
A daily system of muscular contractions, most of them performed lying in bed, rebuilds the aged body and restores it to a youthful condition, as in…
1907 · unreplicated
Soured-milk ('Bulgarian bacillus') longevity therapy
The number of centenarians among Bulgarian peasants is attributable to their consumption of soured milk (yahourth) containing lactic-acid bacteria.
1907 · refuted
Soured-milk ('Bulgarian bacillus') longevity therapy
The large intestine is a part of the body whose putrefactive bacteria release toxins (autointoxication) that are a principal cause of…
1907 · refuted
Soured-milk ('Bulgarian bacillus') longevity therapy
Daily consumption of soured milk fermented with lactic-acid bacteria (the 'Bulgarian bacillus') prolongs human life by arresting the putrefaction of…
1908 · untested
Biologic living (the Battle Creek Idea)
Adopting 'biologic living' (the Battle Creek Idea): an antitoxic vegetarian diet, bowel regularity and colon hygiene, hydrotherapy, exercise, fresh…
1908 · refuted
The Hazzard Fasting Cure
Once the system is cleared of accumulated impurity by fasting, the body is restored to its natural health and vigor, so that periodic fasting is the…
1908 · refuted
The Hazzard Fasting Cure
Fasting cures chronic and organic disease, including conditions that conventional medicine treats as incurable.
1908 · refuted
The Hazzard Fasting Cure
Disease arises when the blood becomes encumbered with impurities and the body succumbs to auto-intoxication; fasting cures disease by suspending…
1910 · refuted
Electronic Reactions of Abrams (ERA)
Every individual, organ, and disease has a constant and specific rate of 'electronic vibration,' so that health and disease are expressions of…
1912 · unreplicated
Bennett's rejuvenation system (muscular contractions and self-massage)
Properly exercising every muscle and organ is the principal secret of health, strength, elasticity of body, and a long life.
1912 · unreplicated
Bennett's rejuvenation system (muscular contractions and self-massage)
Daily facial self-massage and muscular exercise rebuild the muscles beneath the skin, removing wrinkles and sagging and restoring a youthful face.
1912 · refuted
Immortal Cell Culture (Carrel's Chick-Heart Experiment)
Normal tissues, once isolated from the organism and supplied with the correct nutrient medium, can survive and grow indefinitely — cellular death is…
1913 · unreplicated
Fletcherism (thorough mastication)
Mastication restores and preserves youthful strength and endurance into old age, as in Fletcher's own performance in tests of strength at fifty-eight.
1913 · refuted
Fletcherism (thorough mastication)
Thorough mastication ('Fletcherizing') wards off disease and preserves health, conferring a near-freedom from illness.
1916 · refuted
Electronic Reactions of Abrams (ERA)
A single drop of a patient's dried blood (or even the patient's handwriting), placed in the Dynamizer and read through changes in the abdominal…
1916 · refuted
Electronic Reactions of Abrams (ERA)
The Oscilloclast cures disease by broadcasting back at the diseased tissue the same 'electronic vibratory rate' the disease emits, until the patient…
1916 · refuted
Biologic living (the Battle Creek Idea)
Securing frequent bowel evacuation and a 'non-putrefactive' intestinal flora through a high-residue vegetarian diet, bowel training, and colon…
1917 · refuted
Brinkley goat-gland transplantation (goat-to-human gonad implant)
Goat-gland transplantation rejuvenates aging men, restoring youthful vitality and energy and reversing the effects of age.
1917 · refuted
Brinkley goat-gland transplantation (goat-to-human gonad implant)
Surgical implantation of goat gonad tissue restores male sexual function, potency, and fertility in the recipient.
1917 · refuted
Brinkley goat-gland transplantation (goat-to-human gonad implant)
The goat-gland operation is a safe and effective surgical treatment for impotence and the effects of aging.
1919 · refuted
Biologic living (the Battle Creek Idea)
The colon's putrefactive bacteria generate toxins that are absorbed into the body (autointoxication, or intestinal toxemia), and this self-poisoning…
1920 · refuted
Steinach Vasoligation (Steinach Operation)
Obstruction of the vas deferens causes compensatory hypertrophy of the testicular interstitial cells and increases their secretion of rejuvenating…
1920 · refuted
Steinach Vasoligation (Steinach Operation)
Unilateral vasoligation reverses measurable signs of senescence in men, restoring physical vigor, sexual potency, and mental acuity to levels…
1923 · unreplicated
Physical Culture (Macfadden's drugless system)
Macfadden's regimen of fasting, diet, and exercise rejuvenates the body and preserves youthful vigour and long life.
1923 · refuted
Voronoff testicular xenograft (chimpanzee-to-human)
The xenograft procedure as developed and performed by Voronoff is surgically safe and presents no significant risk of disease transmission, immune…
1923 · refuted
Voronoff testicular xenograft (chimpanzee-to-human)
Surgical implantation of chimpanzee testicular tissue restores male sexual function, libido, and physical vigor in the recipient through ongoing…
1924 · refuted
Overbeck's Rejuvenator
Because illness is an imbalance of bodily electricity, the Rejuvenator can treat and relieve almost any complaint, with electrode placements and…
1924 · refuted
Overbeck's Rejuvenator
Applying the Rejuvenator's currents renews the youth and vitality of the old and young alike, restoring the body to a more youthful state.
1924 · unreplicated
Steinach Vasoligation (Steinach Operation)
The Steinach vasoligation is a minor surgical procedure with negligible risk, performed under local anesthesia in under thirty minutes, without…
1925 · refuted
I-ON-A-CO
Worn around the body and connected to the household current, the I-ON-A-CO creates a magnetic field that magnetizes the iron in the body, increasing…
1925 · refuted
I-ON-A-CO
The I-ON-A-CO is a 'New Road to Good Health' that restores the user to perfect health and renewed vitality without bathing, dieting, drugging, or…
1925 · refuted
I-ON-A-CO
By placing the I-ON-A-CO around the neck and turning on the current, the wearer can be rid of any chronic disorder.
1925 · refuted
Overbeck's Rejuvenator
Life consists of appropriate amounts of electricity stored within and passing between the different parts of the body, so that illness is an…
1925 · refuted
Radithor
Daily oral consumption of Radithor will cure or substantially relieve more than 150 conditions, including dyspepsia, hypertension, impotence,…
1925 · refuted
Radithor
Radithor's radium content is at safe 'mild radium therapy' levels; daily consumption presents no significant health risk to the recipient through…
1925 · refuted
Voronoff testicular xenograft (chimpanzee-to-human)
Recipients of Voronoff's testicular xenograft experience meaningful extension of lifespan as a consequence of restored hormonal and cellular function.
1927 · refuted
Radithor
Daily Radithor consumption restores energy, vitality, and sexual function in male recipients, particularly those experiencing age-related decline,…
1928 · untested
Order-energy raw-food regimen (Bircher-Benner's 'Lebendige Kraft' nutrition)
Living by the dietary 'order' of the regimen, eating high in the energy hierarchy on raw plant food, restores the body's living force (Lebendige…
1928 · refuted
Order-energy raw-food regimen (Bircher-Benner's 'Lebendige Kraft' nutrition)
Green plants store the sun's energy, and raw, uncooked plant food carries this living solar energy to the body, so that humans are nourished by…
1929 · refuted
The Hay System (food combining / 'food separation')
Eating concentrated starches and concentrated proteins at separate meals (food separation), while weighting the diet toward base-forming vegetables,…
1929 · untested
The Hay System (food combining / 'food separation')
Hay recounted that after sixteen years of largely surgical practice he 'broke down', developing Bright's disease, high blood pressure, and finally a…
1932 · refuted
Hauser's "Wonder Foods" diet (Look Younger, Live Longer)
Eye exercises (the Bates method), which Hauser promoted in his own 1932 book on vision, can correct refractive error and eliminate the need for…
1935 · refuted
Immortal Cell Culture (Carrel's Chick-Heart Experiment)
Scientific management of human heredity — selecting for biological quality and eliminating the unfit — would maintain the internal environment that…
1935 · refuted
Immortal Cell Culture (Carrel's Chick-Heart Experiment)
Human aging and death are caused by the progressive degeneration of the internal fluid environment surrounding cells, not by any intrinsic limit in…
1935 · refuted
The Hay System (food combining / 'food separation')
Most human disease is one underlying condition: an acidotic, self-poisoning (autointoxication) state produced by wrong eating, of which named…
1939 · refuted
Order-energy raw-food regimen (Bircher-Benner's 'Lebendige Kraft' nutrition)
The nutritive worth of a food is its energetic 'active force', governed by the second principle of thermodynamics, so that foods can be ranked in an…
1939 · untested
Hauser's "Wonder Foods" diet (Look Younger, Live Longer)
Hauser argued that a vitamin-rich diet could maintain glandular youth: Vitamin D for thyroid function, Vitamin B for pituitary regulation, and…
1940 · refuted
Orgone Energy Accumulator
A physically real, undetectable-by-conventional-instrument form of cosmic life energy, which Reich named 'orgone,' pervades the atmosphere;…
1946 · refuted
Antireticular cytotoxic serum (ACS / ATsS)
Antireticular cytotoxic serum is a broad therapeutic agent that accelerates fracture healing, supports postoperative recovery, and serves as an…
1946 · untested
Antireticular cytotoxic serum (ACS / ATsS)
Strengthening the reticular connective tissue with antireticular cytotoxic serum can let people live past one hundred, perhaps as long as one…
1946 · untested
Antireticular cytotoxic serum (ACS / ATsS)
Antireticular cytotoxic serum, given in small therapeutic doses, stimulates the reticuloendothelial system and slows the deterioration of the…
1950 · untested
Hauser's "Wonder Foods" diet (Look Younger, Live Longer)
Eating the five 'wonder foods' -- powdered brewers' yeast, powdered skim milk, yoghourt/yogurt, wheat germ, and black treacle/blackstrap molasses --…
1951 · refuted
Krebiozen Cancer Treatment
Krebiozen produces objective antitumor responses in cancer patients, including measurable tumor reduction and extended survival, as shown by…
1951 · replicated
Krebiozen Cancer Treatment
Andrew Ivy and the Durovic brothers received financial benefit from Krebiozen's distribution, including per-dose patient charges and, in the case of…
1951 · refuted
Krebiozen Cancer Treatment
Krebiozen is derived from the blood of Argentinean horses inoculated with Actinomyces bovis, and contains a naturally occurring anti-cancer…
1951 · refuted
Orgone Energy Accumulator
Sitting in the accumulator is beneficial in the cure, mitigation, treatment, or prevention of an open-ended list of diseases and conditions,…
1953 · refuted
Cellular therapy (Frischzellentherapie)
Injection of fetal sheep cells from a specific organ restores the function and structure of the corresponding aging organ in the recipient through…
1953 · refuted
Cellular therapy (Frischzellentherapie)
Cellular therapy administered to a recipient of advanced age restores youthful function and reverses the visible and felt effects of biological aging.
1953 · refuted
Cellular therapy (Frischzellentherapie)
Cellular therapy as administered at Clinique La Prairie is safe; fresh fetal cells do not provoke meaningful immune rejection in human recipients…
1953 · refuted
Orgone Energy Accumulator
The 'cloudbuster' -- hollow metal pipes connected by cables to a body of water -- can draw excess orgone energy from the atmosphere to relieve…
1954 · refuted
Cellular therapy (Frischzellentherapie)
Cellular therapy administered to Pope Pius XII in 1954 resolved his chronic gastric crisis and produced clinical improvement attributable to the…
1957 · refuted
Gerovital H3 (procaine anti-aging therapy)
Gerovital H3 rejuvenates the aging body, restoring energy, mood, appearance, and sexual vigor.
1957 · refuted
Gerovital H3 (procaine anti-aging therapy)
A course of procaine (Gerovital H3) retards the aging process and prolongs life.
1957 · refuted
Gerovital H3 (procaine anti-aging therapy)
Gerovital H3 treats the chronic diseases of later life, including arthritic, cardiovascular, and other age-related conditions.
1963 · replicated
Krebiozen Cancer Treatment
FDA laboratory analysis of Krebiozen samples found the drug to consist of creatine monohydrate dissolved in mineral oil; some samples contained only…
1970 · refuted
Megadose vitamin C ('orthomolecular' ascorbate therapy)
Regular megadose supplementation with vitamin C (on the order of 1-3 grams per day or more) meaningfully reduces the incidence of the common cold in…
1976 · refuted
Megadose vitamin C ('orthomolecular' ascorbate therapy)
High-dose ascorbate (10 g/day intravenous, then oral maintenance) prolongs survival in terminal cancer patients roughly four-fold compared to…
1990 · unreplicated
Megadose vitamin C ('orthomolecular' ascorbate therapy)
Vitamin C combined with the amino acid lysine (and related lipoprotein(a)-binding inhibitors) prevents and can reverse occlusive cardiovascular…
2002 · untested
Kevin Trudeau Natural Cures infomercial program (2002-2014)
Biotape, a "space age mylar" adhesive strip, connects the body's "broken circuits" to provide permanent relief from severe pain, including…
2002 · refuted
Kevin Trudeau Natural Cures infomercial program (2002-2014)
Coral Calcium Supreme provides the same bioavailable calcium as two gallons of milk, absorbs into the body faster than ordinary calcium, and can…
2003 · refuted
Sirtuin-activating compounds (resveratrol, then NMN)
Resveratrol is 'as close to a miraculous molecule as you can find' — a description Sinclair gave in a 2003 interview with the journal Science,…
2003 · refuted
Sirtuin-activating compounds (resveratrol, then NMN)
Resveratrol directly activates the sirtuin enzyme SIRT1 (and its yeast homolog Sir2), mimicking the life-extending effects of calorie restriction;…
2004 · untested
Kevin Trudeau Natural Cures infomercial program (2002-2014)
There are non-drug, non-surgical natural cures for virtually every disease, and the pharmaceutical industry, the FDA, and the FTC are suppressing…
2006 · refuted
Kevin Trudeau Natural Cures infomercial program (2002-2014)
Following the Weight Loss Cure protocol (daily injections of human chorionic gonadotropin, a hormone produced during pregnancy, alongside a…
2012 · replicated
Kneipp Cure (hydrotherapy, herbalism, and the 'five pillars')
Generic post-exercise cold-water immersion (not the Kneipp-specific regimen) reduces delayed-onset muscle soreness (DOMS) at 24, 48, 72, and 96…
2018 · unreplicated
Sirtuin-activating compounds (resveratrol, then NMN)
Treating aged mice with NMN, a NAD+ precursor, restores capillary density and blood flow and increases exercise endurance by roughly 56-80%,…
2021 · unreplicated
Blueprint (Project Blueprint)
At the launch of Project Blueprint (October 2021), Johnson claimed a measured biological age of 36 against a chronological age of 44, and framed the…
2023 · refuted
Blueprint (Project Blueprint)
Beginning in early 2023, Johnson claimed that exchanging his blood plasma with that of a younger donor (including his then-17-year-old son) would…
2023 · unreplicated
Kneipp Cure (hydrotherapy, herbalism, and the 'five pillars')
Across 20 randomised controlled trials of Kneipp hydrotherapy (132 outcome comparisons), some individual conditions show a significant positive…
2024 · refuted
Sirtuin-activating compounds (resveratrol, then NMN)
A supplement called Leap Years, developed by Animal Bioscience (a company David Sinclair co-founded with his brother Nick Sinclair, its CEO), is…
2024 · untested
Blueprint (Project Blueprint)
Blueprint markets its daily supplement and food stack (including a 'Longevity Mix' powder, 'essential capsules,' and high-polyphenol olive oil) as…
2024 · refuted
Blueprint (Project Blueprint)
Johnson has publicized a claim, widely reported in 2024, that he reduced his 'pace of aging' by 31 years relative to an average person.
2025 · unreplicated
Therapeutic plasma exchange with intravenous immunoglobulin (TPE-IVIG)
Monthly therapeutic plasma exchange without IVIG produces an average 1.32-year reduction in biological age across a panel of 35 epigenetic clocks…
2025 · unreplicated
Therapeutic plasma exchange with intravenous immunoglobulin (TPE-IVIG)
Biweekly therapeutic plasma exchange combined with intravenous immunoglobulin produces an average 2.61-year reduction in biological age as measured…
2025 · unreplicated
Therapeutic plasma exchange with intravenous immunoglobulin (TPE-IVIG)
The TPE-IVIG protocol reverses biological aging in healthy adult recipients, producing measurable rejuvenation across multiple molecular domains…
2026 · unreplicated
Blueprint (Project Blueprint)
As of Blueprint's January 2026 update, Johnson reports an epigenetic 'speed of aging' score of 0.48, telomere length equivalent to a…