METHUSELAH ARCHIVE INGREDIENTS
Ingredients

The active substances.

The materials the interventions were built on — radium, procaine, testicular extract, seawater — and the mechanism each was claimed to work by.
electrical energy
Animal magnetism (proposed universal fluid)
A universal fluid analogous to gravity or electricity flows through and connects all living things. Illness is a blockage or disruption of…
animal tissue
Antireticular cytotoxic serum (ACS / ATsS)
The reticuloendothelial connective tissue is the 'cement' that holds the body together and governs aging. A serum prepared by sensitising…
mineral
Arsenic
Small regular doses were said to stimulate the system, carry off surplus flesh, and clear and whiten the complexion, producing a slender…
synthetic
Ascorbic acid (vitamin C)
At ordinary dietary levels, prevents scurvy. At the multi-gram 'megadose' levels Pauling promoted, claimed to prevent and shorten the…
animal tissue
Beef Extract (Extractum Carnis)
Concentrated water-soluble nitrogenous compounds (albuminoids, creatine, kreatin) representing the nutritive essence of meat; claimed to…
botanical
Blackstrap molasses
That regularly eating black treacle/blackstrap molasses (with powdered brewers' yeast, powdered skim milk, yoghourt/yogurt, and wheat…
animal tissue
Chimpanzee testicular tissue
Live chimpanzee testicular tissue, when surgically implanted under the human scrotal skin, integrates with the recipient and provides…
mineral
Cold water
Cold water, applied to the surface of the body and drunk in quantity, was held to mobilize the morbid or peccant matter responsible for…
mineral
Coral calcium
Infomercials claimed coral calcium supplied the same amount of "bioavailable" calcium as two gallons of milk, was absorbed into the body…
animal tissue
Creatine (Kreatin)
Identified by Liebig and LEMCO as a marker of the nutritive nitrogenous fraction of meat; its presence was taken as evidence that the…
animal tissue
Dog and guinea-pig testicular extract
Extract of freshly removed animal testes contains a 'vital substance' secreted by the testes that diminishes with age and that, when…
human tissue
Donor plasma (in the TPE replacement context)
Removal of aged recipient plasma, with replacement by albumin in saline, reduces circulating inflammatory and senescence-associated…
electrical energy
Electrical Aether (Graham's branded medicine line)
Graham's promotional rhetoric, summarized in Lydia Syson's biography and in Richard C Sha's 2010 *Medical History* review of it, presented…
animal tissue
Fetal sheep cells
Cells from a specific organ of a freshly killed lamb fetus, when injected into a human recipient, will migrate selectively to the…
mineral
Filtered Atlantic seawater (Quinton marine plasma)
Seawater filtered to remove microorganisms and adjusted to isotonic concentration by dilution with distilled water (approximately 9 g/L…
botanical
French brandy (the spirituous base of the Cordial Balm of Gilead)
Brandy is not named in Solomon's advertising, which presents the balm as a preparation of 'the choisest balsams' compounded by long and…
botanical
Gamboge (Garcinia gum-resin purgative)
Within Morison's Hygeian system the pill's vegetable purgatives were held to act by evacuating the impure matter of the blood through the…
animal tissue
Goat gonad tissue
Implanted goat gonad tissue would take root in the human recipient and supply an ongoing glandular stimulus that restored sexual function…
human tissue
Intravenous immunoglobulin (IVIG)
IVIG provides pooled donor-derived antibodies and immunomodulatory factors that, in combination with TPE-mediated removal of aged…
animal tissue
Krebiozen (creatine monohydrate in mineral oil)
Ivy and Durovic claimed Krebiozen stimulated the body's own defenses against cancer through an undefined immunological or enzymatic…
synthetic
NMN (nicotinamide mononucleotide)
Raises cellular NAD+ levels, which in turn is proposed to restore activity of SIRT1 and other sirtuins, repairing age-related declines in…
mineral
Perkins 'special metallic alloy' (claimed)
A proprietary alloy of yellow and white metals, when drawn across the skin, produces a tractive electrical action that draws out the…
electrical energy
Potentized high dilution (Hahnemann's dynamized remedy)
Serial dilution accompanied by vigorous shaking (succussion), a process Hahnemann named potentization or dynamization, was held to release…
synthetic
Procaine hydrochloride (the active component of Gerovital H3)
That a course of injected (and later oral) buffered procaine systemically retards the aging process and treats the chronic diseases of…
radiation
Radium-226 and Radium-228 in distilled water
Low-dose radium ingestion stimulates the endocrine system, increases cellular metabolism, and produces general 'vitality' and restoration…
synthetic
Rapamycin (sirolimus)
Inhibits the mTOR (mechanistic target of rapamycin) signaling pathway, which is proposed to mimic effects of caloric restriction and slow…
botanical
Resveratrol
Activates SIRT1, an NAD+-dependent deacetylase proposed to mediate the lifespan-extending effects of calorie restriction, thereby…
animal tissue
Soured milk fermented with lactic-acid bacteria ('Bulgarian bacillus')
Lactic-acid bacteria introduced into the gut via soured milk produce lactic acid (and, per Metchnikoff's account of Belonowsky's work, a…
animal tissue
Spermine (seminal and tissue polyamine)
Spermin is a catalytic agent that increases oxidation processes in the tissues and acts as a physiological antitoxin against…
mineral
Sulphur-fume-acidulated water (dilute mineral acid)
A gas-charged water that destroys the microbes responsible for every disease, while remaining a harmless, non-poisonous drink that…
botanical
Sunlight nutrition (Sonnenlichtnahrung): solar energy stored in raw plant food
Green plants store the sun's radiant energy through their growth, and raw, uncooked plant food therefore carries the highest charge of…
animal tissue
Testicular Interstitial Cells (Leydig Cells)
Steinach claimed that obstruction of the vas deferens caused atrophy of the sperm-producing seminiferous tubules while causing…
electrical energy
Vital force (Lebenskraft)
An innate vital power animates the living body. Life is the operation of this power; vital operation consumes it; and the duration of life…
synthetic
Wine of Egypt (Cagliostro's rejuvenation elixir)
A few drops of the secret liquid, taken at a prescribed phase of the moon, would rejuvenate the body and restore lost youth; the…