This is Macfadden’s central therapeutic claim, stated in the titles of his own works: fasting, hydropathy, and exercise are “nature’s wonderful remedies for the cure of all chronic and acute diseases” (treatise, c.1900), and Fasting for Health (1923) is “a complete guide on how, when and why to use the fasting cure.” It is classified as mechanism_only: the claim rested on a posited natural-healing mechanism and on Macfadden’s authority and testimony, not on any measured disease outcome. It is recorded as refuted rather than merely untested because fasting is not an accepted treatment for chronic or acute disease in general, the sweeping cure-all framing was never demonstrated by controlled outcome studies, and Macfadden himself died in 1955 after refusing medical treatment for a digestive disorder (Encyclopaedia Britannica), an outcome inconsistent with the disease-curing power the doctrine claimed.