The general rejuvenation claim was the marketing-facing assertion of the Niehans practice and the basis for patient demand. It is grounded in patient self-report and clinic case description; it was never supported by a controlled outcome study during Niehans’s career. In 2015 Swissmedic and the Swiss Federal Office of Public Health reported that fresh-cell therapy had no scientifically demonstrated efficacy. The claim is structurally identical to the rejuvenation assertions of Brown-Séquard (1889) and Voronoff (1920s) and anticipates the contemporary marketing of stem-cell tourism and biological-age-reduction services.