A supplement called Leap Years, developed by Animal Bioscience (a company David Sinclair co-founded with his brother Nick Sinclair, its CEO), is 'the first supplement proven to reverse aging in dogs,' a claim Sinclair made in a company press release and repeated to his roughly 438,000 followers on X in late February 2024.
Not a claim about the case’s core resveratrol/NMN ingredients directly, but the most recent, most sharply documented instance of the case’s promotional pattern: an unpublished, non-peer-reviewed preprint used as the basis for a strong public “reversed aging” claim tied to a commercial product Sinclair co-founded and personally promoted. STAT News reported on 5 March 2024 that no published research had yet demonstrated the claimed effect. University of Washington longevity researcher Matt Kaeberlein, a founding member of the Academy for Health and Lifespan Research that Sinclair then led, publicly resigned his membership over the episode, writing that “I find it deeply distressing that we’ve gotten to a point where dishonesty in science is normalized” and separately calling the episode the textbook case of a scientist selling snake oil. Animal Bioscience subsequently issued a revised press release that stepped away from the age-reversal claim, and Sinclair resigned as the Academy’s president shortly afterward (nmn.com, 7 May 2024). The archive marks the specific “proven to reverse aging” claim refuted on this record.
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- Harvard longevity scientist sparks furor with claim about reversing aging in dogs — Molteni, Megan. Harvard longevity scientist sparks furor with claim about reversing aging in dogs. STAT News, 5 March 2024.
- After careful consideration, I have renounced my membership in the Academy for Health and Lifespan Research. — Kaeberlein, Matt. LinkedIn post, 3 March 2024.
- Dr. David Sinclair Steps Down from Prominent Aging Research Academy — Weiss, Brett J. Dr. David Sinclair Steps Down from Prominent Aging Research Academy. NMN.com, 7 May 2024 (updated 17 May 2024).