METHUSELAH ARCHIVE SOURCES / MILAZZO-SYSTEMATIC-REVIEW-LAETRILE-2007

Laetrile for Cancer: A Systematic Review of the Clinical Evidence

clinical paper · 2007
type:clinical paper
year:2007
citation:Milazzo S, Lejeune S, Ernst E. Laetrile for Cancer: A Systematic Review of the Clinical Evidence. Supportive Care in Cancer 15, no. 6 (June 2007): 583-595. PMID: 17106659. DOI: 10.1007/s00520-006-0168-9.
LINK
https://pubmed.ncbi.nlm.nih.gov/17106659/
SUMMARY
Systematic review of 36 reports containing clinical data on laetrile interventions (no controlled clinical trials found among them; three nonconsecutive case series, two consecutive case series, six best-case series, and 25 case reports). Conclusion, per its indexed abstract: none of the 36 reports proved laetrile's effectiveness, and the claim that laetrile benefits cancer patients is not supported by sound clinical data. PMID 17106659 confirmed via PubMed/NCBI eutils esummary and Crossref DOI resolution; abstract wording per EXA-indexed abstract text, not independently re-fetched from a directly loaded PubMed page (PubMed's page presented a cookie-consent interstitial to automated fetch during this research session).
NOTES

An earlier systematic review by the same lead author as the 2011 Cochrane review, documenting that the entire pre-2007 clinical literature on laetrile outside the 1982 NCI-sponsored trial consists of uncontrolled case reports and case series.