2,4-Dinitrophenol (DNP): A Weight Loss Agent with Significant Acute Toxicity and Risk of Death
clinical paper · 2011
SUMMARY
Comprehensive modern toxicological review tracing DNP's history from 1930s marketing through its post-2000 internet-driven resurgence as a bodybuilding and slimming aid; records very few reported deaths from the late 1930s until the 2000s, and counts 62 published deaths attributed to DNP in the medical literature, followed by a marked recent increase in deaths tied to online availability; states there is no specific antidote for DNP poisoning; as of its 2011 publication, a primary authority establishing that the post-2000 online market is a direct continuation of the same substance and marketing claim first disconfirmed in 1938.
NOTES
Comprehensive peer-reviewed clinical toxicology review establishing the causal and historical continuity between the 1930s DNP episode and its modern online resurgence, and documenting the absence of a safe dose or antidote.