METHUSELAH ARCHIVE SOURCES / FREDERICK-CANCER-GOV-IV-VITAMIN-C-2020

Intravenous High-Dose Vitamin C in Cancer Therapy

secondary literature · 2020
type:secondary literature
year:2020
citation:Cantley L, Yun J. Intravenous High-Dose Vitamin C in Cancer Therapy. Frederick National Laboratory for Cancer Research, 24 January 2020.
LINK
https://frederick.cancer.gov/node/7313
SUMMARY
An NCI-affiliated laboratory's explainer on the history and current status of high-dose vitamin C in cancer therapy. Byline (Lewis Cantley and Jihye Yun) and publication date (24 January 2020) confirmed by direct fetch of the page. Summarizes the Cameron-Pauling 1976/1978 PNAS studies' retrospective, non-placebo-controlled design; contrasts it with the Mayo Clinic's randomized double-blind trials and the two studies' differing treatment durations and administration routes; and states plainly that because the Mayo trials were more rigorous, 'people trusted the Mayo Clinic's data and discredited the Cameron-Pauling trials, dampening the enthusiasm for vitamin C as a cancer therapy.'
NOTES

The clearest single secondary source tying together the original claim, its design flaws, and its rebuttal, from an NCI-affiliated research institution. Quotes verified in a verify-quotes block in research/notes/grounding-pauling-vitamin-c-megadose-1970-present.md.