METHUSELAH ARCHIVE SOURCES / ATSDR-TOXICOLOGICAL-PROFILE-DINITROPHENOLS

Toxicological Profile for Dinitrophenols

government report · 2019
type:government report
year:2019
citation:Agency for Toxic Substances and Disease Registry (ATSDR), U.S. Department of Health and Human Services, Toxicological Profile for Dinitrophenols, 2019, https://www.atsdr.cdc.gov/toxprofiles/tp64.pdf (see also NCBI Bookshelf edition, https://www.ncbi.nlm.nih.gov/books/NBK590059/)
SUMMARY
Federal toxicological reference profile stating: 'In 1938, the FDA declared DNP to be extremely dangerous and not fit for human consumption, and use of 2,4-DNP was discontinued due to serious adverse health effects, including fatality.' Documents chronic effects including cataracts and other adverse effects, and states that, while no longer used in medicine, 'the compound is still marketed for weight loss by unregulated internet sources.'
NOTES

Authoritative U.S. government toxicological reference establishing the 1938 FDA prohibition and the chronic/acute harm profile, and recording that, as of its 2019 profile, DNP was ‘still marketed for weight loss by unregulated internet sources.’