Origin of the So-Called Auto-Intoxication Symptoms
clinical paper · 1919
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SUMMARY
Alvarez's 1919 JAMA paper is the contemporaneous clinical refutation of the autointoxication theory on which Tyrrell's device depended. Alvarez argued that the symptoms attributed to 'autointoxication' did not arise from the absorption of putrefactive products from the bowel in the harmful quantities the theory required, undermining the premise that retained intestinal waste poisons the body and shortens life. Identifiers confirmed against the Crossref record (DOI 10.1001/jama.1919.02610010014002): author Walter C. Alvarez, JAMA volume 72, issue 1, page 8, published 4 January 1919. This is the same critic the archive's Metchnikoff case cites for the empirical collapse of the autointoxication framework.
NOTES
The Alvarez 1919 JAMA paper is the appropriate period source for the empirical disconfirmation of the theory underlying the J.B.L. Cascade. Walter C. Alvarez, an internal-medicine physician, challenged the central claim of the autointoxication school, that toxins from retained intestinal waste are absorbed and cause systemic disease and premature aging, on the ground that the gut does not absorb putrefactive products in the quantities the theory demanded. The paper is one of the most-cited contemporary critiques and is the same disconfirming reference used in this archive’s Metchnikoff case for the same theory. Identifiers confirmed against Crossref (DOI 10.1001/jama.1919.02610010014002).