Ana Aslan
Ana Aslan (1 January 1897, Braila, to 20 May 1988, Bucharest) was a Romanian physician who became the international face of procaine therapy for aging. Working under the gerontologist Constantin Ion Parhon, she repurposed buffered procaine (the local anesthetic Novocain) as a systemic anti-aging agent, branded Gerovital H3, from around 1949 to 1951. She directed the National Institute of Geriatrics and Gerontology in Bucharest (its director from 1958 until her death) and organized the Romanian Society of Gerontology and Geriatrics in 1959, building Gerovital into a national geriatric program that drew foreign patients to Romania.
Her own 1965 Journal of Gerontology paper reported that long-term procaine extended the lifespan of albino rats, the experimental basis for the human anti-aging claim. The systemic human evidence was reviewed and rejected by Ostfeld, Smith, and Stotsky in 1977, who found no convincing value beyond a possible antidepressant effect. Aslan died in 1988; the Gerovital name survives on two tracks, as a procaine-free Romanian cosmetic line (Farmec) and as a procaine medicine, a 2% procaine hydrochloride Gerovital H3 injectable bearing her name and manufactured by Zentiva, documented as commercially available under a Romanian marketing authorization in a 2020 study. The geriatric institute she led continues to operate under her name.